Calibre can't email-connection issue

Any idea why I'm having problems sending a newspaper download to my Kindle?
Here is the connection failed message:

calibre, version 0.8.30
ERROR: Failed to email book: <b>Failed</b>: Email The Sydney Morning Herald - Printed edition [Fri, 16 Dec 2011] to myemailaddress@kindle.com

Starting job: Email The Sydney Morning Herald - Printed edition [Fri, 16 Dec 2011] to myemailaddress@kindle.com

Sending failed...

Traceback (most recent call last):
File "site-packages/calibre/gui2/email.py", line 37, in run
File "site-packages/calibre/gui2/email.py", line 112, in sendmail
File "site-packages/calibre/utils/smtp.py", line 93, in sendmail
File "site-packages/calibre/utils/smtp.py", line 85, in sendmail_direct
IOError: Failed to send mail: error(61, 'Connection refused')


Retrying in 1 seconds...


Sending failed...

Traceback (most recent call last):
File "site-packages/calibre/gui2/email.py", line 37, in run
File "site-packages/calibre/gui2/email.py", line 112, in sendmail
File "site-packages/calibre/utils/smtp.py", line 93, in sendmail
File "site-packages/calibre/utils/smtp.py", line 85, in sendmail_direct
IOError: Failed to send mail: error(60, 'Operation timed out')

Job: "Email The Sydney Morning Herald - Printed edition [Fri, 16 Dec 2011] to myemailaddress@kindle.com" failed with error:
Traceback (most recent call last):
File "site-packages/calibre/gui2/threaded_jobs.py", line 83, in start_work
File "site-packages/calibre/gui2/email.py", line 92, in __call__
IOError: Failed to send mail: error(60, 'Operation timed out')

Called with args: (u'/var/folders/rs/b3c8wqn937xbh801d6y_tq140000gn/T/calibre_0.8.30_tmp_5tBi6L/1EV9Y3caltmpfmt.mobi', u'The Sydney Morning Herald - Printed edition [Fri, 16 Dec 2011] - calibre.mobi', u'alexkindle_68@kindle.com', u'E-book: The Sydney Morning Herald - Printed edition [Fri, 16 Dec 2011]', u'Attached, you will find the e-book\n\nThe Sydney Morning Herald - Printed edition [Fri, 16 Dec 2011]\n\tby calibre\n\nin the MOBI format.') {u'notifications': <Queue.Queue instance at 0x113d2fb48>, u'abort': <threading._Event object at 0x1131f00d0>, u'log': <calibre.utils.logging.GUILog object at 0x113d70190>}


Thanks guys.